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Analysis and minimization of cellular RNA editing by DNA adenine base editors.

Rees HA, Wilson C, Doman JL, Liu DR
Sci Adv. 2019 May 8;5(5):eaax5717. doi: 10.1126/sciadv.aax5717. eCollection 2019 May. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
125647pCMV-ABEmaxAWExpresses ABEmaxAW in mammalian cells
125648pCMV-ABEmax(TadA E59A)Expresses ABEmax(TadA E59A) in mammalian cells
125649pCMV-ABEmax(TadA E59A, TadA*E59A)pCMV-ABEmax(TadA E59A, TadA*E59A) in mammalian cells
125650pCMV-ABEmax(TadA E59A, TadA*V106M)pCMV-ABEmax(TadA E59A, TadA*V106M) in mammalian cells
125651pCMV-ABEmax(TadA E59A, TadA*V106Q)pCMV-ABEmax(TadA E59A, TadA*V106Q) in mammalian cells
125652pCMV-ABEmax(TadA E59A, TadA*V106F)pCMV-ABEmax(TadA E59A, TadA*V106F) in mammalian cells
125653pCMV-ABEmax(TadA E59A, TadA*D108W)pCMV-ABEmax(TadA E59A, TadA*D108W) in mammalian cells
125654pCMV-ABEmax(TadA E59A, TadA*D108F)pCMV-ABEmax(TadA E59A, TadA*D108F) in mammalian cells
125655pCMV-ABEmax(TadA E59A, TadA*D108Q)pCMV-ABEmax(TadA E59A, TadA*D108Q) in mammalian cells
125656pCMV-ABEmax(TadA E59A, TadA*D108M)pCMV-ABEmax(TadA E59A, TadA*D108M) in mammalian cells
125657pCMV-ABEmax(TadA E59A, TadA*R47Q)pCMV-ABEmax(TadA E59A, TadA*R47Q) in mammalian cells
125658pCMV-ABEmax(TadA E59A, TadA*R47F)pCMV-ABEmax(TadA E59A, TadA*R47F) in mammalian cells
125659pCMV-ABEmax(TadA E59A, TadA*R47W)pCMV-ABEmax(TadA E59A, TadA*R47W) in mammalian cells
125660pCMV-ABEmax(TadA E59A, TadA*R47M)pCMV-ABEmax(TadA E59A, TadA*R47M) in mammalian cells
125661pCMV-TadA-TadA*Expresses the TadA-TadA* dimer in mammalian cells
125662pCMV-ABEmax(TadA, TadA*E59A)pCMV-ABEmax(TadA, TadA*E59A) in mammalian cells
126496pCMV-ABEmax(TadA E59Q, TadA* V106W)Expresses ABEmax(TadA E59Q, TadA*V106W) in mammalian cells
126497pCMV-ABEmax(TadA E59, TadA* V106W)Expresses ABEmax(TadA E59, TadA*V106W) in mammalian cells

Antibodies from Article