CREB-activity and nmnat2 transcription are down-regulated prior to neurodegeneration, while NMNAT2 over-expression is neuroprotective, in a mouse model of human tauopathy.
Ljungberg MC, Ali YO, Zhu J, Wu CS, Oka K, Zhai RG, Lu HC
Hum Mol Genet. 2012 Jan 15;21(2):251-67. doi: 10.1093/hmg/ddr492. Epub 2011 Oct 25.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 124970 | AV4-EF1-NMNAT2 | Express NMNAT2 |
| 124971 | AV4-EF1-GFP | Control for AV4-EF1-NMNAT2 |