Prohibitin is a prognostic marker and therapeutic target to block chemotherapy resistance in Wilms' tumor.

Ortiz MV, Ahmed S, Burns M, Henssen AG, Hollmann TJ, MacArthur I, Gunasekera S, Gaewsky L, Bradwin G, Ryan J, Letai A, He Y, Naranjo A, Chi YY, LaQuaglia M, Heaton T, Cifani P, Dome JS, Gadd S, Perlman E, Mullen E, Steen H, Kentsis A
JCI Insight. 2019 Aug 8;4(15). pii: 127098. doi: 10.1172/jci.insight.127098. eCollection 2019 Aug 8. PubMed Article

Plasmids from Article

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ID	Plasmid	Purpose
122233	pLKO-PHB-8	Expresses shRNA targeting the coding sequence of human PHB
122232	pLKO-PHB-6	Expresses shRNA targeting the coding sequence of human PHB
122231	pLKO-PHB-4	Expresses shRNA targeting the 3' UTR of human PHB
122230	plx304-PHB-V5	Expresses human PHB attached to a V5 tag