Interrogating the protein interactomes of RAS isoforms identifies PIP5K1A as a KRAS-specific vulnerability.
Adhikari H, Counter CM
Nat Commun. 2018 Sep 7;9(1):3646. doi: 10.1038/s41467-018-05692-6.
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PubMed
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 122208 | pcDNA3.1-myc-BirA*-KRASG12V | Expresses myc-BirA* fused to KRASG12V in mammalian cells |
| 122209 | pcDNA3.1-myc-BirA*-NRASG12V | Expresses myc-BirA* fused to NRASG12V in mammalian cells |
| 122211 | mycBioID-pBabePuro-myc-BirA*KRASG12V | Stably expresses myc-BirA* fused to KRASG12V in mammalian cells |
| 122212 | mycBioID-pBabePuro-myc-BirA*NRASG12V | Stably expresses myc-BirA* fused to NRASG12V in mammalian cells |
| 122214 | mycBioID-pBabePuro-myc-BirA*HRASG12V | Stably expresses myc-BirA* fused to HRASG12V in mammalian cells |