A regulatable AAV vector mediating GDNF biological effects at clinically-approved sub-antimicrobial doxycycline doses.
Chtarto A, Humbert-Claude M, Bockstael O, Das AT, Boutry S, Breger LS, Klaver B, Melas C, Barroso-Chinea P, Gonzalez-Hernandez T, Muller RN, DeWitte O, Levivier M, Lundberg C, Berkhout B, Tenenbaum L
Mol Ther Methods Clin Dev. 2016 Mar 30;5:16027. doi: 10.1038/mtm.2016.27. eCollection 2016.
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PubMed
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 122033 | pAC1-V16-eGFP | AAV vector, pTet bidi (bidirectional tetracycline-responsive promoter) driving Tet-dependent rtTA and eGFP expression |
| 122034 | pAC1-V16-Luc | AAV vector, pTet bidi (bidirectional tetracycline-responsive promoter) driving Tet-dependent rtTA and Luciferase expression |
| 122035 | pAC1-V16-hGDNF | AAV vector, pTet bidi (bidirectional tetracycline-responsive promoter) driving Tet-dependent rtTA and hGDNF expression |