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Human iPSC-based modeling of late-onset disease via progerin-induced aging.

Miller JD, Ganat YM, Kishinevsky S, Bowman RL, Liu B, Tu EY, Mandal PK, Vera E, Shim JW, Kriks S, Taldone T, Fusaki N, Tomishima MJ, Krainc D, Milner TA, Rossi DJ, Studer L
Cell Stem Cell. 2013 Dec 5;13(6):691-705. doi: 10.1016/j.stem.2013.11.006. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
140189pLenti-hSyn-PROGERINOverexpression of Progerin with a GFP fusion protein, under human synapsin promotor
140190pLenti-hSyn-nucGFPOverexpression of GFP with a nuclear localization sequence, under the human synapsin promoter

Antibodies from Article