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Oncoprotein CIP2A is stabilized via interaction with tumor suppressor PP2A/B56.

Wang J, Okkeri J, Pavic K, Wang Z, Kauko O, Halonen T, Sarek G, Ojala PM, Rao Z, Xu W, Westermarck J
EMBO Rep. 2017 Mar;18(3):437-450. doi: 10.15252/embr.201642788. Epub 2017 Feb 7. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
119287pcDNA3.1/CIP2A(1-905) WT V5 HisCIP2A WT V5 overexpression
119288pcDNA3.1/CIP2A(1-905) L533E V5 HisCIP2A L533E V5 overexpression, CIP2A dimer defective mutant
119289pcDNA3.1/CIP2A(1-905) R522D V5 HisCIP2A R522D V5 overexpression, CIP2A dimer defective mutant

Antibodies from Article