Phosphorylation of serine 303 is a prerequisite for the stress-inducible SUMO modification of heat shock factor 1.
Hietakangas V, Ahlskog JK, Jakobsson AM, Hellesuo M, Sahlberg NM, Holmberg CI, Mikhailov A, Palvimo JJ, Pirkkala L, Sistonen L
Mol Cell Biol. 2003 Apr . 23(8):2953-68.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 118360 | hSUMO1 GFP | This plasmid expresses the full length human SUMO1. |
| 118361 | hSUMO1-HIS | This plasmid expresses the full length human SUMO1. |
| 118362 | hHSF1 K298R | This plasmid expresses human HSF1 K298R mutant, which cannot undergo sumoylation on K298. |
| 118363 | hHSF1 S303A | This plasmid expresses human HSF1 S303A mutant, which cannot undergo sumoylation on K298 due to disrupted PDSM motif. |
| 118364 | hHSF1 S307A | This plasmid expresses human HSF1 S307A mutant. |
| 118365 | hHSF1 S303/7A | This plasmid expresses human HSF1 S303A and S307A mutant, which cannot undergo sumoylation on K298 due to disrupted PDSM motif. |