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The interaction of Epac1 and Ran promotes Rap1 activation at the nuclear envelope.

Liu C, Takahashi M, Li Y, Dillon TJ, Kaech S, Stork PJ
Mol Cell Biol. 2010 Aug;30(16):3956-69. doi: 10.1128/MCB.00242-10. Epub 2010 Jun 14. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
118315GFP-RalGDSExpression of human RalGDS
118316mCherry-RanV19Expression of human Ran
118317GFP-RanV19 E1RA2Expression of human Ran
118319mCherry-Rap1bExpression of bovine Rap1b
118320mCherry-Rap2bExpression of human Rap2b
118321GFP-Rap2bExpression of human Rap2b
118322Flag-Rap1b N17Expression of bovine Rap1b
118323Flag-Rap1b V12Expression of bovine Rap1b
118324Flag-RapGAPExpression of RapGAP

Antibodies from Article