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Imaging of morphological and biochemical hallmarks of apoptosis with optimized optogenetic tools.

Godwin WC, Hoffmann GF, Gray TJ, Hughes RM
J Biol Chem. 2019 Nov 8;294(45):16918-16929. doi: 10.1074/jbc.RA119.009141. Epub 2019 Oct 3. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
117238Cry2(1-531)-mCh-BAXS184ELight activated recruitment of BAX in mammalian cells with Cry2/CIB optogenetic switch
117239Cry2L348F(1-531)-mCh-BAXS184ELight activated recruitment of BAX in mammalian cells with Cry2/CIB optogenetic switch
117242Tom20-CIB-GFPLight activated recruitment to OMM in mammalian cells with Cry2/CIB optogenetic switch
117243Tom20-CIB-stopLight activated recruitment to OMM in mammalian cells with Cry2/CIB optogenetic switch

Antibodies from Article