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The oncogenic potential of the Pax3-FKHR fusion protein requires the Pax3 homeodomain recognition helix but not the Pax3 paired-box DNA binding domain.

Lam PY, Sublett JE, Hollenbach AD, Roussel MF
Mol Cell Biol. 1999 Jan;19(1):594-601. (Link opens in a new window) PubMed

Plasmids from Article

ID Plasmid Purpose
115526pCDNA3-PAX3-FOXO1/FKHRMammalian expression construct

Antibodies from Article