Mouse medulloblastoma driven by CRISPR activation of cellular Myc.
Vo BT, Kwon JA, Li C, Finkelstein D, Xu B, Orr BA, Sherr CJ, Roussel MF
Sci Rep. 2018 Jun 7;8(1):8733. doi: 10.1038/s41598-018-24956-1.
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PubMed
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 114726 | pT2K-CAGGS-U6-stuffer-dCAs9-VP160-T2A-IRES-mCherry | dCas9-VP160 expression in mammalian cells |
| 114727 | pT2K-CAGGS-U6-stuffer (infusion)-IRES-CFP | expression in mammalian cells |
| 114728 | pT2K-CAGGS-U6-sgRNA-M5-IRES-CFP | sgRNA targeting a sequence upstream of the initiator ATG of the cellular Myc gene |
| 114729 | pT2K-CAGGS-U6-sgRNA-M5-U6-sgRNA-M7-U6-sgRNA-M9-IRES-CFP | 3 sgRNAs targeting a sequence upstream of the initiator ATG of the cellular Myc gene |
| 114730 | pT2K-CAGGS-U6-sgRNA-M7-IRES-CFP | sgRNA targeting a sequence upstream of the initiator ATG of the cellular Myc gene |
| 114731 | pT2K-CAGGS-U6-sgRNA-M9-IRES-CFP | sgRNA targeting a sequence upstream of the initiator ATG of the cellular Myc gene |