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An evolutionarily conserved gene family encodes proton-selective ion channels.

Tu YH, Cooper AJ, Teng B, Chang RB, Artiga DJ, Turner HN, Mulhall EM, Ye W, Smith AD, Liman ER
Science. 2018 Mar 2;359(6379):1047-1050. doi: 10.1126/science.aao3264. Epub 2018 Jan 25. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
114674mOtop1_pGEMHEThis construct was used to express mouse Otop1 in Xenopus laevis oocytes
114675mOtop2_pGEMHEThis construct was used to express mouse Otop2 in Xenopus laevis oocytes
114676mOtop3_pGEMHEThis construct was used to express mouse Otop3 in Xenopus laevis oocytes
114677mOtop1_pcDNA3This construct was used to express mouse Otop1 in HEK-293 cells
114678mOtop2_pcDNA3This construct was used to express mouse Otop2 in HEK-293 cells
114679mOtop3_pcDNA3This construct was used to express mouse Otop3 in HEK-293 cells

Antibodies from Article