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A Family of Vertebrate-Specific Polycombs Encoded by the LCOR/LCORL Genes Balance PRC2 Subtype Activities.

Conway E, Jerman E, Healy E, Ito S, Holoch D, Oliviero G, Deevy O, Glancy E, Fitzpatrick DJ, Mucha M, Watson A, Rice AM, Chammas P, Huang C, Pratt-Kelly I, Koseki Y, Nakayama M, Ishikura T, Streubel G, Wynne K, Hokamp K, McLysaght A, Ciferri C, Di Croce L, Cagney G, Margueron R, Koseki H, Bracken AP
Mol Cell. 2018 May 3;70(3):408-421.e8. doi: 10.1016/j.molcel.2018.03.005. Epub 2018 Apr 5. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
114441pCR8 LCOREntry vector for gateway cloning containing human LCOR coding sequence
114442pCR8 PALI1Entry vector for gateway cloning containing human PALI1 coding sequence
114443pCR8 JARID2Entry vector for gateway cloning containing human JARID2 coding sequence
114444pLENTI EF1alpha FLAG/HA-LCORMammalian lentiviral expression vector containing N terminal FLAG/HA tagged human LCOR coding sequence
114445pLENTI EF1alpha FLAG/HA-PALI1Mammalian lentiviral expression vector containing N terminal FLAG/HA tagged human PALI1 coding sequence
114449pVL-FLAG/His PALI1Insect baculovirus expression vector containing N terminal FLAG/His tagged human PALI1 coding sequence
114450pVL-FLAG/His LCORInsect baculovirus expression vector containing N terminal FLAG/His tagged human LCOR coding sequence

Antibodies from Article