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A Suite of Transgenic Driver and Reporter Mouse Lines with Enhanced Brain-Cell-Type Targeting and Functionality.

Daigle TL, Madisen L, Hage TA, Valley MT, Knoblich U, Larsen RS, Takeno MM, Huang L, Gu H, Larsen R, Mills M, Bosma-Moody A, Siverts LA, Walker M, Graybuck LT, Yao Z, Fong O, Nguyen TN, Garren E, Lenz GH, Chavarha M, Pendergraft J, Harrington J, Hirokawa KE, Harris JA, Nicovich PR, McGraw MJ, Ollerenshaw DR, Smith KA, Baker CA, Ting JT, Sunkin SM, Lecoq J, Lin MZ, Boyden ES, Murphy GJ, da Costa NM, Waters J, Li L, Tasic B, Zeng H
Cell. 2018 Jul 12;174(2):465-480.e22. doi: 10.1016/j.cell.2018.06.035. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
114426Ai139 (TIT2L-GFP-ICL-TPT) targeting vectorTarget a Cre-dependent GFP and a tdTomato-P2A-tTA2 expression cassette into the mouse TIGRE locus
114427Ai140 (TIT2L-GFP-ICL-tTA2) targeting vectorTarget a Cre-dependent GFP and a tTA2 expression cassette into the mouse TIGRE locus
114428Ai148 (TIT2L-GC6f-ICL-tTA2) targeting vectorTarget a Cre-dependent GCaMP6f expression and a tTA2 cassette into the mouse TIGRE locus
114429Ai161 (TIT2L-GFP-ICR-tTA2) targeting vectorTarget a Cre-dependent GFP cassette and Dre-dependent tTA2 cassette to the mouse TIGRE locus
114430Ai163 (TIT2L-GC6s-ICL-TPT) targeting vectorTarget a Cre-dependent GCaMP6s cassette and a tdTomato-P2A-tTA2 cassette to the mouse TIGRE locus
114431Ai167 (TIT2L-ChrimsonR-tdT-ICL-tTA2) targeting vectorTarget a Cre-dependent ChrimsonR-tdTomato cassette and a tTA2 cassette into the mouse TIGRE locus
114432Ai133 (TITL-ssAPEX2tm) targeting vectorTarget a Cre-dependent electron microscopy tag ssAPEX2tm cassette into the mouse TIGRE locus
114433Ai162 (TIT2L-GC6s-ICL-tTA2) targeting vectorTarget a Cre-dependent GCaMP6s cassette and a tTA2 cassette into the mouse TIGRE locus
114435Ai170 (TIT2L-ASAP2s-Kv-ICL-tTA2) targeting vectorTarget a Cre-dependent voltage sensor ASAP2s cassette into the mouse TIGRE locus
114438Calb1-T2A-dgCre targeting vectorTarget dgCre into the endogenous mouse Calb1 locus at the stop codon

Antibodies from Article