Chromosomal instability by inefficient Mps1 auto-activation due to a weakened mitotic checkpoint and lagging chromosomes.
Jelluma N, Brenkman AB, McLeod I, Yates JR 3rd, Cleveland DW, Medema RH, Kops GJ
PLoS One. 2008 Jun 11;3(6):e2415. doi: 10.1371/journal.pone.0002415.
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Plasmids from Article
ID | Plasmid | Purpose |
---|---|---|
114065 | pFastBac-GST-Mps1-WT | protein production |
114066 | pFastBac-GST-Mps1-KD | protein production |