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AC6 is the major adenylate cyclase forming a diarrheagenic protein complex with cystic fibrosis transmembrane conductance regulator in cholera.

Thomas A, Ramananda Y, Mun K, Naren AP, Arora K
J Biol Chem. 2018 Jun 14. pii: RA118.003378. doi: 10.1074/jbc.RA118.003378. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
113903pTriEx4-ADCY6-C1(306-672 aa)His-S tagged cytoplasmic catalytic domain 1 of Adenylate Cyclase 6
113904pTriEx4-ADCY6-C2 (917-1165 aa)His-S tagged cytoplasmic catalytic domain 2 of Adenylate Cyclase 6
113905pAmCyan1-C1-ADCY6N-terminal Cyan Fluorescent tag in Adenylate Cyclase 6

Antibodies from Article