Intrinsic differences between FVIIIa mimetic bispecific antibodies and FVIII prevent assignment of FVIII-equivalence.
Leksa NC, Aleman MM, Goodman A, Rabinovich D, Peters R, Salas J
J Thromb Haemost. 2019 Mar 18. doi: 10.1111/jth.14430.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 113664 | anti-FIX(a) Emi HC | For transient expression of Emicizumab sequence (CAS# 1610943-06-0, KEGG# D10821), IgG4 bispecific antibody targeting FIX(a) & FX(a). Must be co-expressed with the anti-FX(a) Emi HC and the Emi LC. |
| 113665 | anti-FX(a) Emi HC | For transient expression of Emicizumab sequence (CAS# 1610943-06-0, KEGG# D10821), IgG4 bispecific antibody targeting FIX(a) & FX(a). Must be co-expressed with the anti-FIX(a) Emi HC and the Emi LC. |
| 113666 | Emi LC | For transient expression of Emicizumab sequence (CAS# 1610943-06-0, KEGG# D10821), IgG4 bispecific antibody targeting FIX(a) & FX(a). Must be co-expressed with anti-FIX(a) and anti-FX(a) Emi HC's. |