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Chimeric antigen receptors that trigger phagocytosis.

Morrissey MA, Williamson AP, Steinbach AM, Roberts EW, Kern N, Headley MB, Vale R
Elife. 2018 Jun 4;7. pii: 36688. doi: 10.7554/eLife.36688. (Link opens in a new window) PubMed

Plasmids from Article

ID Plasmid Purpose
113013pHR CD19-mMegf10 CARfor production of lentivirus encoding the CD19 CAR-Pmegf10
113014pHR CD19-FcGamma CARfor production of lentivirus encoding the CD19 CAR-Pfcgamma
113016pHR CD22-Megf10 CARfor production of lentivirus encoding CD22 CAR-P Megf10
113018pHR CD19-PI3K CARfor lentivirus production of CD19-PI3K CAR
113019pHR CD19 tandem CARfor lentivirus production of CD19 tandem CAR
113020pHR GFP-CaaXfor lentivirus production of GFP-CaaX
113021pET28 His10-FcRɣfor purification of His10-FcRɣ intracellular domain
113028pGEX6-2 SNAP-Syk tSH2for purification of Syk tSh2. Purified protein will have a snap tag that can be conjugated to fluorescent dyes.
113030pHR OVA/p2a/mCherry-CaaXfor lentivirus production of ovalbumin and mcherry-caax

Antibodies from Article