Adenine base editing in mouse embryos and an adult mouse model of Duchenne muscular dystrophy.
Ryu SM, Koo T, Kim K, Lim K, Baek G, Kim ST, Kim HS, Kim DE, Lee H, Chung E, Kim JS
Nat Biotechnol. 2018 Jul;36(6):536-539. doi: 10.1038/nbt.4148. Epub 2018 Apr 27.
(Link opens in a new window)
PubMed
(Link opens in a new window)
Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 112734 | pAAV-ABE-NT-sgRNA | AAV inverted terminal repeat based vector plasmid encoding E. coli TadA, the N-terminal half of nCas9 and sgRNA |
| 112876 | pAAV-ABE-CT | AAV inverted terminal repeat based vector plasmid encoding the C-terminal half of nCas9 |
| 113128 | p3s-ABE7.10 | expressing ABE7.10 (TadA-TadA*7.10-nCas9-NLS-HA), human codon optimized |