Locus-specific DNA methylation of Mecp2 promoter leads to autism-like phenotypes in mice.
Lu Z, Liu Z, Mao W, Wang X, Zheng X, Chen S, Cao B, Huang S, Zhang X, Zhou T, Zhang Y, Huang X, Sun Q, Li JD
Cell Death Dis. 2020 Feb 3;11(2):85. doi: 10.1038/s41419-020-2290-x.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 112209 | pSt1374-N-NLS-DNMT3L-L-DNMT3Amut-L-dcas9-NLS | Targeted DNA methylation |
| 112210 | pSt1374-N-NLS-DNMT3L-L-DNMT3A-L-dcas9-NLS | Targeted DNA methylation |
| 112211 | pAAV-CAG-C-intein-C-spC9-H840A-N863A-2xNLS-hGH | Targeted DNA methylation |
| 112212 | pAAV-CAG-NLS-DNMT3A-L-N-spC9-N-intein-hGH | Targeted DNA methylation |
| 112213 | pAAV-5U6-sgRNAs-hsyn-EGFP | Targeted DNA methylation |
| 112214 | pSt1374m-EF1alpha-N-NLS-DNMT3L-L-DNMT3A-L-dcas9-NLS | Targeted DNA methylation |
| 112215 | pSt1374m-EF1alpha-N-NLS-DNMT3L-L-DNMT3Amut-L-dcas9-NLS | Targeted DNA methylation |