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KRAS Dimerization Impacts MEK Inhibitor Sensitivity and Oncogenic Activity of Mutant KRAS.

Ambrogio C, Kohler J, Zhou ZW, Wang H, Paranal R, Li J, Capelletti M, Caffarra C, Li S, Lv Q, Gondi S, Hunter JC, Lu J, Chiarle R, Santamaria D, Westover KD, Janne PA
Cell. 2018 Feb 8;172(4):857-868.e15. doi: 10.1016/j.cell.2017.12.020. Epub 2018 Jan 11. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
112717pcDNA3.1-CFP-KRAS4BExpresses CFP-KRAS4B fusion protein used for FRET studies in mammalian cells.
112718pcDNA3.1-YFP-KRAS4BExpresses YFP-KRAS4B fusion protein used for FRET studies in eukaryotic cells.

Antibodies from Article