Perturbed Wnt signaling leads to neuronal migration delay, altered interhemispheric connections and impaired social behavior.
Bocchi R, Egervari K, Carol-Perdiguer L, Viale B, Quairiaux C, De Roo M, Boitard M, Oskouie S, Salmon P, Kiss JZ
Nat Commun. 2017 Oct 27;8(1):1158. doi: 10.1038/s41467-017-01046-w.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 27246 | pCLX-UBI-Tred | |
| 114276 | pCWXPGR-pTF-DVL2deltaDIX | TET-inducible expression of DVL2 protein with a deletion of its DIX-domain |
| 114277 | pCWXPGR-pTF-dnTCF4 | TET-inducible expression of a dominant negative form of the TCF4 transcription factor |
| 114283 | pCLXEBR-pTF-hM3Dq | TET-inducible expression of the hM3Dq protein |
| 114287 | pCWXPGR-pTF-Wnt3a | TET-inducible expression of Wnt3a |
| 114293 | pCLXEBR-pTF-cKit | TET-inducible expression of c-Kit |
| 114294 | pCLX-MIFE-hM3Dq-PGK-mCherry | Mifepristone-inducible expression of hM3Dq protein |
| 114322 | pCLX-G4E1b-R1DESTR2-MIFE-PGK-mCherry | Mifepristone-inducible lentiviral backbone for Gateway cloning of Gene insert together with constitutive mCherry expression |