Janus-faced Sestrin2 controls ROS and mTOR signalling through two separate functional domains.
Kim H, An S, Ro SH, Teixeira F, Park GJ, Kim C, Cho CS, Kim JS, Jakob U, Lee JH, Cho US
Nat Commun. 2015 Nov 27;6:10025. doi: 10.1038/ncomms10025.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 111776 | pLU-CMV-Flag-hSesn2 WT | Mammalian expression or 3rd generation lentivirus generation of hSesn2 |
| 111777 | pLU-CMV-Flag-hSesn2 C125S | Mammalian expression or 3rd generation lentivirus generation of hSesn2 |
| 111778 | pLU-CMV-Flag-hSesn2 L128C/H113E | Mammalian expression or 3rd generation lentivirus generation of hSesn2 |
| 111779 | pLU-CMV-Flag-hSesn2 P87S | Mammalian expression or 3rd generation lentivirus generation of hSesn2 |
| 111780 | pLU-CMV-Flag-hSesn2 H132A | Mammalian expression or 3rd generation lentivirus generation of hSesn2 |
| 111781 | pLU-CMV-Flag-hSesn2 Y127F | Mammalian expression or 3rd generation lentivirus generation of hSesn2 |
| 111782 | pLU-CMV-Flag-hSesn2 C204S | Mammalian expression or 3rd generation lentivirus generation of hSesn2 |
| 111783 | pLU-CMV-Flag-hSesn2 C399S | Mammalian expression or 3rd generation lentivirus generation of hSesn2 |
| 111784 | pLU-CMV-Flag-hSesn2 R264P | Mammalian expression or 3rd generation lentivirus generation of hSesn2 |
| 111786 | pLU-CMV-Flag-hSesn2 C430S | Mammalian expression or 3rd generation lentivirus generation of hSesn2 |
| 111787 | pLU-CMV-Flag-hSesn2 T336A/F337A | Mammalian expression or 3rd generation lentivirus generation of hSesn2 |
| 111788 | pLU-CMV-Flag-hSesn2 Q340A/D341A | Mammalian expression or 3rd generation lentivirus generation of hSesn2 |
| 111789 | pLU-CMV-Flag-hSesn2 L373A/N376A/D385A/S387A | Mammalian expression or 3rd generation lentivirus generation of hSesn2 |
| 111790 | pLU-CMV-Flag-hSesn2 R404A/D406A/D407A | Mammalian expression or 3rd generation lentivirus generation of hSesn2 |
| 111791 | pLU-CMV-Flag-hSesn2 D409A/G411A/Q415A | Mammalian expression or 3rd generation lentivirus generation of hSesn2 |
| 111792 | pLU-CMV-Flag-hSesn2 R419A | Mammalian expression or 3rd generation lentivirus generation of hSesn2 |
| 111793 | pLU-CMV-Flag-hSesn2 R419A/K422A/K426A | Mammalian expression or 3rd generation lentivirus generation of hSesn2 |
| 111794 | pLU-CMV-Flag-hSesn2 D406A | Mammalian expression or 3rd generation lentivirus generation of hSesn2 |
| 111795 | pLU-CMV-Flag-hSesn2 D407A | Mammalian expression or 3rd generation lentivirus generation of hSesn2 |