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The tale of two talins - two isoforms to fine-tune integrin signalling.

Gough RE, Goult BT
FEBS Lett. 2018 May 3. doi: 10.1002/1873-3468.13081. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
111028mTalin2_F0Plasmid expresses mouse talin2 FERM domain F0
111029mTalin2_F1Plasmid expresses mouse talin2 FERM domain F1
111030mTalin2_F2Plasmid expresses mouse talin2 FERM domain F2
111031mTalin2_F3Plasmid expresses mouse talin2 FERM domain F3
111032mTalin2_NeckPlasmid expresses the unstructured neck region of mouse talin2
111033mTalin2_R1Plasmid expresses the talin2 rod domain R1 a 5 helix bundle.
111034mTalin2_R2Plasmid expresses the talin2 rod sub domain R2 a 4 helix bundle.
111035mTalin2_R3Plasmid expresses the talin2 rod sub domain R3 a 4 helix bundle.
111036mTalin2_R4Plasmid expresses the talin2 rod sub domain R4 a 4 helix bundle.
111037mTalin2_R5Plasmid expresses the talin2 rod domain R5 a 5 helix bundle.
111038mTalin2_R6Plasmid expresses the talin2 rod domain R6 a 5 helix bundle.
111040mTalin2_R8Plasmid expresses the talin2 rod domain R8 a 4 helix bundle.
111042mTalin2_R9Plasmid expresses the talin2 rod domain R9 a 5 helix bundle.
111043mTalin2_R10Plasmid expresses the talin2 rod domain R10 a 5 helix bundle.
111044mTalin2_R11Plasmid expresses the talin2 rod domain R11 a 5 helix bundle.
111045mTalin2_R12Plasmid expresses the talin2 rod domain R12 a 5 helix bundle.
111046mTalin2_R13Plasmid expresses the talin2 rod domain R13 a 5 helix bundle.
111047mTalin2_R13-DDPlasmid expresses the talin2 rod domain R13 and the dimerisation domian DD.

Antibodies from Article