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Thioredoxin-1 protects against androgen receptor-induced redox vulnerability in castration-resistant prostate cancer.

Samaranayake GJ, Troccoli CI, Huynh M, Lyles RDZ, Kage K, Win A, Lakshmanan V, Kwon D, Ban Y, Chen SX, Zarco ER, Jorda M, Burnstein KL, Rai P
Nat Commun. 2017 Oct 31;8(1):1204. doi: 10.1038/s41467-017-01269-x. (Link opens in a new window) PubMed

Plasmids from Article

ID Plasmid Purpose
110919pblic-neo TRX1To overexpress Thioredoxin-1
110920plko-tet-on-puromycin-shTRX1-259To knockdown Thioredoxin-1 following doxycycline addition

Antibodies from Article