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Truncated CPSF6 forms higher order complexes that bind and disrupt HIV-1 capsid.

Ning J, Zhong Z, Fischer DK, Harris G, Watkins SC, Ambrose Z, Zhang P
J Virol. 2018 Apr 11. pii: JVI.00368-18. doi: 10.1128/JVI.00368-18. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
110693pSICO-CPSF6-358-eGFPExpresses a truncated form of CPSF6 (CPSF6-358 originally described in Lee et al. Cell Host Microbe 2010) fused with eGFP
110694pSICO-CPSF6-358-iRFP670Expresses a truncated form of CPSF6 (CPSF6-358 originally described in Lee et al. Cell Host Microbe 2010) fused with iRFP670

Antibodies from Article