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Generation of a neutralizing antibody against RD114-pseudotyped viral vectors.

Mekkaoui L, Ferrari M, Mattiuzzo G, Ma B, Nannini F, Onuoha S, Kotsopoulou E, Takeuchi Y, Pule M
J Gen Virol. 2019 Nov 8. doi: 10.1099/jgv.0.001309. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
110555MP28444 – pFUSE2ss-aRD114_CHIg-mIgG2ApFUSE backbone with an IL2 signal sequence, expressing the variable heavy chain of anti-RD114 binder fused to murine IgG2A constant heavy chain.
110556MP28445 – pFUSE2ss-aRD114_CLIg-mIgKpFUSE backbone with an IL2 signal sequence, expressing the variable light chain of anti-RD114 binder fused to murine Kappa constant light chain.

Antibodies from Article