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The ubiquitin ligase CRL2ZYG11 targets cyclin B1 for degradation in a conserved pathway that facilitates mitotic slippage.

Balachandran RS, Heighington CS, Starostina NG, Anderson JW, Owen DL, Vasudevan S, Kipreos ET
J Cell Biol. 2016 Oct 24;215(2):151-166. Epub 2016 Oct 17. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
110550pFLAG-ZYG11Bexpresses a FLAG-tagged human ZYG11B protein in mamalian cells
110551pFLAG-ZYG11Aexpresses a FLAG-tagged human ZYG11A protein in mamalian cells

Antibodies from Article