Radically truncated MeCP2 rescues Rett syndrome-like neurological defects.
Tillotson R, Selfridge J, Koerner MV, Gadalla KKE, Guy J, De Sousa D, Hector RD, Cobb SR, Bird A
Nature. 2017 Oct 19;550(7676):398-401. doi: 10.1038/nature24058. Epub 2017 Oct 11.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 110186 | pEGFP-N1_MeCP2(WT) | Expression of mouse MeCP2 (WT) in mammalian cells |
| 110187 | pEGFP-N1_MeCP2(R111G) | Expression of mouse MeCP2 (R111G) in mammalian cells |
| 110188 | pEGFP-N1_MeCP2(R306C) | Expression of mouse MeCP2 (R306C) in mammalian cells |
| 110189 | pEGFP-N1_MeCP2(deltaN) | Expression of mouse MeCP2 (deltaN) in mammalian cells |
| 110190 | pEGFP-N1_MeCP2(deltaNC) | Expression of mouse MeCP2 (deltaNC) in mammalian cells |
| 110191 | pEGFP-N1_MeCP2(deltaNIC) | Expression of mouse MeCP2 (deltaNIC) in mammalian cells |