Functional genomic screen in mesothelioma reveals that loss of function of BRCA1-associated-protein-1 induces chemoresistance to ribonucleotide reductase inhibition.
Okonska A, Buhler S, Rao V, Ronner M, Blijlevens M, van der Meulen-Muileman IH, de Menezes RX, Wipplinger M, Oehl K, Smit EF, Weder W, Stahel RA, Penengo L, van Beusechem VW, Felley-Bosco E
Mol Cancer Ther. 2019 Oct 16. pii: 1535-7163.MCT-19-0356. doi: 10.1158/1535-7163.MCT-19-0356.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 108438 | BAP1-C91A (siRNA resistant) | Stable expression of BAP1-C91A (catalytically inactive mutant) in mammalian cells, gene has an introduced siRNA-resistance against siBAP1. |
| 108439 | BAP1-wt (siRNA resistant) | Stable expression of BAP1-wt in mammalian cells, gene has an introduced siRNA-resistance against siBAP1. |
| 108440 | BAP1-C91A | Stable expression of BAP1-C91A in mammalian cells. |