Adoptive transfer of syngeneic T cells transduced with a chimeric antigen receptor that recognizes murine CD19 can eradicate lymphoma and normal B cells.
Kochenderfer JN, Yu Z, Frasheri D, Restifo NP, Rosenberg SA
Blood. 2010 Nov 11;116(19):3875-86. doi: 10.1182/blood-2010-01-265041. Epub 2010 Jul 14.
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Plasmids from Article
ID | Plasmid | Purpose |
---|---|---|
107226 | MSGV-1D3-28Z All ITAMs intact | Anti-mouse CD19 CAR with CD3 ITAMs intact |
107227 | MSGV1-1D3-28Z.1-3 mut | Anti-mouse CD19 CAR with CD3 ITAMs mutated |