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Lipid binding promotes the open conformation and tumor-suppressive activity of neurofibromin 2.

Chinthalapudi K, Mandati V, Zheng J, Sharff AJ, Bricogne G, Griffin PR, Kissil J, Izard T
Nat Commun. 2018 Apr 6;9(1):1338. doi: 10.1038/s41467-018-03648-4. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
107148pET32a-Trx-PP-hNF2bacterial expression
107149PGEX-6P1-hNF2-AR mutantbacterial expression
107150pcDNA3-Flag-hNF2mammalian expression

Antibodies from Article