Oncogenic RAS Signaling Promotes Tumor Immunoresistance by Stabilizing PD-L1 mRNA.
Coelho MA, de Carne Trecesson S, Rana S, Zecchin D, Moore C, Molina-Arcas M, East P, Spencer-Dene B, Nye E, Barnouin K, Snijders AP, Lai WS, Blackshear PJ, Downward J
Immunity. 2017 Dec 19;47(6):1083-1099.e6. doi: 10.1016/j.immuni.2017.11.016. Epub 2017 Dec 12.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 107000 | pTRIPZ Myc2-mouse TTP WT | Expresses epitope-tagged wild-type murine TTP |
| 107001 | pTRIPZ Myc2-mouse TTP aa S52 S178 MUT | Expresses epitope-tagged double-mutant murine TTP |
| 107002 | pGL3 1kb prom. CD274 | Modified Luciferase expression vector |
| 107003 | pGL3 2 kb prom. CD274 | Modified Luciferase expression vector |
| 107004 | pGL3 3 kb prom. CD274 | Modified Luciferase expression vector |
| 107005 | pGL3 1 kb prom. + Enhancer CD274 | Modified Luciferase expression vector |
| 107006 | pGL3 1 kb prom and exon1 fragment CD274 | Modified Luciferase expression vector |
| 107007 | pGL3 2 kb prom. and exon 1 fragment CD274 | Modified Luciferase expression vector |
| 107008 | pcDNA3 Myc2- Hs TTP WT | Expresses epitope-tagged wild-type human TTP |
| 107009 | pGL3 3'UTR reporter WT 1.3 kb CD274 Hs 3'UTR Final | Modified Luciferase expression vector |
| 107010 | pGL3 3'UTR reporter MUT 1.3 kb CD274 Hs 3'UTR Final | Modified Luciferase expression vector |
| 107012 | pUNO mouse CD274 + 3'UTR WT full length | Expresses murine PD-L1 with the 3'UTR |