Sestrin as a feedback inhibitor of TOR that prevents age-related pathologies.
Lee JH, Budanov AV, Park EJ, Birse R, Kim TE, Perkins GA, Ocorr K, Ellisman MH, Bodmer R, Bier E, Karin M
Science. 2010 Mar 5;327(5970):1223-8. doi: 10.1126/science.1182228.
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Plasmids from Article
ID | Plasmid | Purpose |
---|---|---|
66919 | pGEX-4T-1 dSesn (1187) | bacterial expression of dSesn |
66920 | pUAST-Myc-mSesn2 (1186) | expression of mouse Sesn2 in drosophila |