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Parkinson disease mutant E46K enhances alpha-synuclein phosphorylation in mammalian cell lines, in yeast, and in vivo.

Mbefo MK, Fares MB, Paleologou K, Oueslati A, Yin G, Tenreiro S, Pinto M, Outeiro T, Zweckstetter M, Masliah E, Lashuel HA
J Biol Chem. 2015 Apr 10;290(15):9412-27. doi: 10.1074/jbc.M114.610774. Epub 2015 Feb 5. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
105728pT7-7 asyn E46KBacterial expression of mutant human alpha synuclein
105729pcDNA6 asyn A30PMammalian expression of mutant human alpha synuclein
105730pcDNA6 asyn E46KMammalian expression of mutant human alpha synuclein
107425pcDNA6 asyn WTMammalian expression of human alpha synuclein

Antibodies from Article