Cx32 hemichannel opening by cytosolic Ca2+ is inhibited by the R220X mutation that causes Charcot-Marie-Tooth disease.
Carrer A, Leparulo A, Crispino G, Ciubotaru CD, Marin O, Zonta F, Bortolozzi M
Hum Mol Genet. 2017 Oct 25. pii: 4565496. doi: 10.1093/hmg/ddx386.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 78150 | pIRES2Cx32WTEGFP | Mammalian Expression of Connexin 32 and EGFP from a bicistronic mRNA |
| 78151 | Cx32R220stop | Mammalian Expression of the first 219 amino acids of Connexin 32 and EGFP from a bicistronic mRNA |