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Identification of Chemical Inhibitors of beta-Catenin-Driven Liver Tumorigenesis in Zebrafish.

Evason KJ, Francisco MT, Juric V, Balakrishnan S, Lopez Pazmino Mdel P, Gordan JD, Kakar S, Spitsbergen J, Goga A, Stainier DY
PLoS Genet. 2015 Jul 2;11(7):e1005305. doi: 10.1371/journal.pgen.1005305. eCollection 2015 Jul. (Link opens in a new window) PubMed

Plasmids from Article

ID Plasmid Purpose
105127pKE4-I-SceI-fabp10a:Xpt-β-cat, cryaa:VenusUsed along with I-SceI enzyme to generate transgenic zebrafish expressing hepatocyte-specific Xenopus activated beta-catenin and lens-specific Venus fluorescent protein

Antibodies from Article