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ER-mitochondria tethering by PDZD8 regulates Ca(2+) dynamics in mammalian neurons.

Hirabayashi Y, Kwon SK, Paek H, Pernice WM, Paul MA, Lee J, Erfani P, Raczkowski A, Petrey DS, Pon LA, Polleux F
Science. 2017 Nov 3;358(6363):623-630. doi: 10.1126/science.aan6009. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
105005pCAG-PDZD8HAMammalian Expression of PDZD8
105006pCAG-PDZD8HA_sh_resistantMammalian Expression of PDZD8, sh resistant
105007pCAG-AKAP-mtagBFP2-UBC6Mammalian Expression of mtagBFP2
105012pCAG G-CEPIA1erER calcium sensor
105013pCAG mito-RCaMP1hmitochondrial calcium sensor
105014pCAG cyto-RCaMP1hcytosolic calcium sensor

Antibodies from Article