NFS1 undergoes positive selection in lung tumours and protects cells from ferroptosis.
Alvarez SW, Sviderskiy VO, Terzi EM, Papagiannakopoulos T, Moreira AL, Adams S, Sabatini DM, Birsoy K, Possemato R
Nature. 2017 Nov 22. doi: 10.1038/nature24637.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 102963 | pLKO.1P shNFS1_1 | Suppression of NFS1 |
| 102964 | pLKO.1P shNFS1_2 | Suppression of NFS1 |
| 102965 | pLKO.1P shNFS1_3 | Suppression of NFS1 |
| 102966 | pLKO.1P shNFS1_4 | Suppression of NFS1 |
| 102967 | pLKO.1P shNfs1 | Suppression of mNfs1 |
| 102968 | pLKO.1P shABCB7_1 | Suppression of ABCB7 |
| 102969 | pLKO.1P shABCB7_2 | Suppression of ABCB7 |
| 102970 | pLKO.1P shFXN_1 | Suppression of FXN |
| 102971 | pLKO.1P shFXN_2 | Suppression of FXN |
| 102972 | pLKO.1P shISCU | Suppression of ISCU |
| 102973 | pLKO.1P shMOCS3_1 | Suppression of MOCS3 |
| 102974 | pLKO.1P shMOCS3_2 | Suppression of MOCS3 |
| 102975 | pLKO.1P shSOD1 | Suppression of SOD1 |
| 102976 | pLKO.1P shSOD2 | Suppression of SOD2 |
| 102977 | pBabe hygro NFS1 | Expression of NFS1 |
| 102978 | pBabe hygro NFS1 CD | Expression of NFS1 C381A mutant |
| 102979 | pLENTICRISPR sgNFS1 | Cutting NFS1 genomic locus |