Engineering a light-activated caspase-3 for precise ablation of neurons in vivo.
Smart AD, Pache RA, Thomsen ND, Kortemme T, Davis GW, Wells JA
Proc Natl Acad Sci U S A. 2017 Sep 26;114(39):E8174-E8183. doi: 10.1073/pnas.1705064114. Epub 2017 Sep 11.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 104628 | LIC1B_Caspase-LOVN7C-7 C450A | bacterial expression of light-activated caspase-3 with N7C-7 linker variation on C450A mutation |
| 104629 | LIC1B_Caspase-LOVN7C-7 | bacterial expression of light-activated caspase-3 with N7C-7 linker variation |