Biochemical and Structural Analysis of Common Cancer-Associated KRAS Mutations.
Hunter JC, Manandhar A, Carrasco MA, Gurbani D, Gondi S, Westover KD
Mol Cancer Res. 2015 Sep;13(9):1325-35. doi: 10.1158/1541-7786.MCR-15-0203. Epub 2015 Jun 2.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 111848 | pDNA2.0 6H-FLAG-TEV-KRAS G12C | Expresses activated human KRAS G12C (amino acids 1 - 169) in E. coli with amino terminal 6xHIS and FLAG tags that can be removed with TEV protease. |
| 111849 | pDNA2.0 6H-TEV-KRAS | Expresses wild type human KRAS (amino acids 1 - 169) in E. coli with amino terminal 6xHIS tag that can be removed with TEV protease. |
| 111850 | pDNA2.0 6H-TEV-KRAS G12V | Expresses activated human KRAS G12V (amino acids 1 - 169) in E. coli with amino terminal 6xHIS tag that can be removed with TEV protease. |
| 111851 | pDNA2.0 6H-TEV-KRAS G13D | Expresses activated human KRAS G13D (amino acids 1 - 169) in E. coli with amino terminal 6xHIS tag that can be removed with TEV protease. |