CRISPR/Cas9-Mediated Knockin Application in Cell Therapy: A Non-viral Procedure for Bystander Treatment of Glioma in Mice.
Meca-Cortes O, Guerra-Rebollo M, Garrido C, Borros S, Rubio N, Blanco J
Mol Ther Nucleic Acids. 2017 Sep 15;8:395-403. doi: 10.1016/j.omtn.2017.07.012. Epub 2017 Jul 18.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 104397 | pCRISPR-Cas9/CD4-TK2 | The designed sgRNA cloned into this plasmid directs the specific DNA cleavage exerted by Cas9 nuclease in a region of exon 5 of the human TK2 gene. The plasmid also includes the Cas9 nuclease and CD4. |