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An RNA polymerase II-driven Ebola virus minigenome system as an advanced tool for antiviral drug screening.

Nelson EV, Pacheco JR, Hume AJ, Cressey TN, Deflube LR, Ruedas JB, Connor JH, Ebihara H, Muhlberger E
Antiviral Res. 2017 Aug 12;146:21-27. doi: 10.1016/j.antiviral.2017.08.005. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
103049pCAGGS_NP_EBOVEncodes Ebola virus NP gene (Zaire ebolavirus, Mayinga) under control of the CAG promoter
103050pCAGGS_VP35_EBOVEncodes Ebola virus VP35 gene (Zaire ebolavirus, Mayinga) under control of the CAG promoter
103051pCAGGS_VP30_EBOVEncodes Ebola virus VP30 gene (Zaire ebolavirus, Mayinga) under control of the CAG promoter
103052pCAGGS_L_EBOVEncodes Ebola virus L gene (Zaire ebolavirus, Mayinga) under control of the CAG promoter
103054pCAGGS_3E5E_eGFPEncodes Ebola virus minigenome with EGFP reporter gene. Minigenome is under control of the CAG promoter
103055pCAGGS_3E5E_luciferaseEncodes Ebola virus minigenome with firefly luciferase reporter gene. Minigenome is under control of the CAG promoter

Antibodies from Article