Permanent farnesylation of lamin A mutants linked to progeria impairs its phosphorylation at serine 22 during interphase.
Moiseeva O, Lopes-Paciencia S, Huot G, Lessard F, Ferbeyre G
Aging (Albany NY). 2016 Feb;8(2):366-81.
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Plasmids from Article
ID | Plasmid | Purpose |
---|---|---|
73810 | Progerin-S22D-CS-pLPC | Progerin mutant where Serine 22 is mutated to aspartic acid and where there is a substitution of cysteine in CaaX-motif by a serine |