Genome-scale measurement of off-target activity using Cas9 toxicity in high-throughput screens.
Morgens DW, Wainberg M, Boyle EA, Ursu O, Araya CL, Tsui CK, Haney MS, Hess GT, Han K, Jeng EE, Li A, Snyder MP, Greenleaf WJ, Kundaje A, Bassik MC
Nat Commun. 2017 May 5;8:15178. doi: 10.1038/ncomms15178.
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Plasmids from Article
ID | Plasmid | Purpose |
---|---|---|
101926 | Bassik lab Human CRISPR-Cas9 Deletion Library - Apoptosis and cancer | Bassik lab Human CRISPR-Cas9 Deletion Library - Apoptosis and cancer. Coexpresses mCherry. |
101927 | Bassik lab Human CRISPR-Cas9 Deletion Library - Drug targets, kinases, phosphatases | Bassik lab Human CRISPR-Cas9 Deletion Library - Drug targets, kinases, phosphatases. Coexpresses mCherry. |
101928 | Bassik lab Human CRISPR-Cas9 Deletion Library - Gene Expression | Bassik lab Human CRISPR-Cas9 Deletion Library - Gene Expression. Coexpresses mCherry. |
101929 | Bassik lab Human CRISPR-Cas9 Deletion Library - Membrane proteins | Bassik lab Human CRISPR-Cas9 Deletion Library - Membrane proteins. Coexpresses mCherry. |
101930 | Bassik lab Human CRISPR-Cas9 Deletion Library - Proteostasis | Bassik lab Human CRISPR-Cas9 Deletion Library - Proteostasis. Coexpresses mCherry. |
101931 | Bassik lab Human CRISPR-Cas9 Deletion Library - Trafficking, mitochondrial, motility | Bassik lab Human CRISPR-Cas9 Deletion Library - Trafficking, mitochondrial, motility. Coexpresses mCherry. |
101932 | Bassik lab Human CRISPR-Cas9 Deletion Library - Unassigned1 | Bassik lab Human CRISPR-Cas9 Deletion Library - Unassigned1. Coexpresses mCherry. |
101933 | Bassik lab Human CRISPR-Cas9 Deletion Library - Unassigned2 | Bassik lab Human CRISPR-Cas9 Deletion Library - Unassigned2. Coexpresses mCherry. |
101934 | Bassik lab Human CRISPR-Cas9 Deletion Library - Unassigned3 | Bassik lab Human CRISPR-Cas9 Deletion Library - Unassigned3. Coexpresses mCherry. |