A Becn1 mutation mediates hyperactive autophagic sequestration of amyloid oligomers and improved cognition in Alzheimer's disease.
Rocchi A, Yamamoto S, Ting T, Fan Y, Sadleir K, Wang Y, Zhang W, Huang S, Levine B, Vassar R, He C
PLoS Genet. 2017 Aug 14;13(8):e1006962. doi: 10.1371/journal.pgen.1006962. eCollection 2017 Aug.
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PubMed
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 99505 | lenti-HA-mBec1 | 3rd generation lentiviral expression of wild-type Becn1 |
| 99506 | lenti-HA-mBec1 F121A | Lentiviral expression of mutant Becn1 leading to hyperactive autophagy |