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REST suppression mediates neural conversion of adult human fibroblasts via microRNA-dependent and -independent pathways.

Drouin-Ouellet J, Lau S, Brattas PL, Rylander Ottosson D, Pircs K, Grassi DA, Collins LM, Vuono R, Andersson Sjoland A, Westergren-Thorsson G, Graff C, Minthon L, Toresson H, Barker RA, Jakobsson J, Parmar M
EMBO Mol Med. 2017 Aug;9(8):1117-1131. doi: 10.15252/emmm.201607471. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
101852U6REST1_U6REST2.hPGK.BRN2.hPGK.Ascl1WPREDirect reprogramming of adult fibroblasts to neurons
127573pLKO.1-REST_sh_seq1_WPREshRNA to knock down RE1-silencing transcription factor (REST)
127574pLKO.1REST_sh_seq2_WPREshRNA to knock down RE1-silencing transcription factor (REST)

Antibodies from Article