Phosphoglycerol dihydroceramide, a distinctive ceramide produced by Porphyromonas gingivalis, promotes RANKL-induced osteoclastogenesis by acting on non-muscle myosin II-A (Myh9), an osteoclast cell fusion regulatory factor.
Kanzaki H, Movila A, Kayal R, Napimoga MH, Egashira K, Dewhirst F, Sasaki H, Howait M, Al-Dharrab A, Mira A, Han X, Taubman MA, Nichols FC, Kawai T
Biochim Biophys Acta. 2017 May;1862(5):452-462. doi: 10.1016/j.bbalip.2017.01.008. Epub 2017 Jan 31.
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