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Kruppel-like factor 4 (KLF4) regulates the miR-183~96~182 cluster under physiologic and pathologic conditions.

Segura MF, Jubierre L, Li S, Soriano A, Koetz L, Gaziel-Sovran A, Masanas M, Kleffman K, Dankert JF, Walsh MJ, Hernando E
Oncotarget. 2017 Apr 18;8(16):26298-26311. doi: 10.18632/oncotarget.15459. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
100126pGL4-Cluster Promoter Delta 1It contains ~1.4Kb of the miR-183/96-182 cluster promoter
100127pGL4-Cluster Promoter Delta 2It contains ~4.8 Kb of the miR-183-96-182 cluster promoter
100128pGL4-Cluster Promoter Delta 3It contains ~2.7 Kb of the miR-183-96-182 cluster promoter
100129pGL4-Cluster Promoter Delta 1.1It contains ~0.8 Kb of the miR-183-96-182 cluster promoter. Is the minimal region that contains the maximal promoter activity
100130pGL4 Cluster Promoter Delta 1.2It contains 0.5 Kb of the miR-183-96-182 cluster promoter. This fragment partially loses promoter activity in melanoma cells.
100131pEIGW-human KLF4Human KLF4 lentiviral expression vector

Antibodies from Article